|本期目录/Table of Contents|

[1]肖艳华,崔猛,李艳艳.红花的化学成分[J].武汉工程大学学报,2014,(03):15-17.[doi:103969/jissn16742869201403003]
　XIAO Yan hua,CUI Meng,LI Yan yan.Chemical constituents of Safflower carthamus[J].Journal of Wuhan Institute of Technology,2014,(03):15-17.[doi:103969/jissn16742869201403003]
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《武汉工程大学学报》[ISSN:1674-2869/CN:42-1779/TQ]

卷:
期数:
2014年03期
页码:
15-17
栏目:
化学与化学工程
出版日期:
2014-03-31

文章信息/Info

Title:
Chemical constituents of Safflower carthamus
文章编号:
16742869(2014)03001503
作者:
肖艳华; 崔猛; 李艳艳
武汉工程大学化工与制药学院，湖北 武汉430074
Author(s):
XIAO Yanhua; CUI Meng; LI Yanyan
School of Chemical Engineering & Pharmacy,Wuhan Institute of Technology,Wuhan 430074,China;
关键词:
红花; 化学成分; 分离纯化; 香豆素
Keywords:
Safflower carthamus; chemical constituents; separation and purification; coumarin
分类号:
TQ463+.6
DOI:
103969/jissn16742869201403003
文献标志码:
A
摘要:
红花资源丰富且有悠久的民间用药历史，为了寻找其活性成分，丰富红花化合物的类型，对红花的化学成分进行系统的研究.用体积分数75%乙醇提取红花，所得浸膏以水稀释，再以石油醚、氯仿、乙酸乙酯和正丁醇萃取，对氯仿和乙酸乙酯部分浓缩所得浸膏以各种硅胶柱色谱和分离纯化，利用溶解性、颜色反应等理化性质以及红外光谱、质谱及氢(1)核磁共振等波谱数据确定了所得物质的结构.从红花中分离并鉴定了3个化合物，分别为:3（3′,4′二甲氧基苯基）7羟基8（3甲基丁基）香豆素(1),1（2吡啶基）3戊酮(2),α甲氧基苯乙酸1十一烷基十二烷酯(3).这3个化合物均为首次从该植物中分离得到.
Abstract:
Safflower carthamus is rich in resources and has a long medication history.To find the active ingredient and enrich the types of compounds,a systematic research on its chemical constituents were carried out.The chemical constituents of S.carthamus were extracted by 75% ethanol.The residue was suspended in water and then extracted successively with Petroleum ether,chloroform,ethyl acetate and nbutanol.Chloroform part and ethyl acetate part were isolated and purified by silica gel column chromatography and recrystallization.Their structures were characterized by solubility,chromogenic reaction,infrared,mass spectrometry and 1H NMR.Three compounds including Coumarin,3(3′,4′ dimethoxyphenyl) 7hydroxyl 8(3 methylbuthyl)(1),3Pentone,1(2pyridinyl)(2),Benzeneacetic acid,αmethoxy1undecyldodecyl ester(3) were isolated and identified.All of them were obtained from this plant for the first time.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期：20131216作者简介：肖艳华 (1971)，女，湖北武汉人，副教授,博士.研究方向:药物合成、天然药物提取分离和活性研究以及精细化学品研发.
更新日期/Last Update: 2014-04-18