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[1]巨修练,胡福临,王均震,等.环氧虫啉的晶体结构及其杀虫活性[J].武汉工程大学学报,2013,(12):17-21.[doi:103969/jissn16742869201312004]
　JU Xiu\|lian,HU Fu\|lin,WANG Jun\|zhen,et al.Crystal structure and insecticidal activity of huanyangchonglin[J].Journal of Wuhan Institute of Technology,2013,(12):17-21.[doi:103969/jissn16742869201312004]
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环氧虫啉的晶体结构及其杀虫活性(/HTML)
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《武汉工程大学学报》[ISSN:1674-2869/CN:42-1779/TQ]

卷:
期数:
2013年12期
页码:
17-21
栏目:
化学与化学工程
出版日期:
2013-12-31

文章信息/Info

Title:
Crystal structure and insecticidal activity of huanyangchonglin
文章编号:
16742869(2013)12001705
作者:
巨修练1; 胡福临1; 王均震2; 李黎3; 李水清3
1. 武汉工程大学化工与制药学院,教育部绿色化工过程重点实验室,湖北 武汉 430074; 2. 武汉信佳和诚药物化学有限公司,湖北 武汉 430075; 3. 武汉中鑫化工有限公司,湖北 武汉 430200
Author(s):
JU Xiu\|lian1; HU Fu\|lin1; WANG Jun\|zhen2; LI Li3; LI Shui\|qing3
1. Key laboratory for Green Chemical Process of Ministry of Education,School of Chemical Engineering and Pharmacy,Wuhan Institute of Technology,Wuhan 430074,China; 2. Wuhan Synchallenge Unipharm Inc.,Ltd.,Wuhan 430075,China; 3. Wuhan Zhongxin Chemical Co.Ltd.,Wuhan 430200,China
关键词:
新烟碱类;  晶体结构;  单晶衍射
Keywords:
neonicotinoids;  crystal structure;  X\|ray diffraction
分类号:
O621.4
DOI:
103969/jissn16742869201312004
文献标志码:
A
摘要:
新烟碱类杀虫剂环氧虫啉由武汉工程大学和武汉中鑫化工有限公司联合研制.为了促进环氧虫啉的开发及应用，采用一步合成法，将环氧氯丙烷与2\|硝基亚氨基咪唑烷合成环氧虫啉.环氧虫啉纯化后，通过挥发法培养得到环氧虫啉单晶，并用核磁共振氢谱、质谱、元素分析和X\|射线单晶衍射等手段进行表征.最后，对环氧虫啉的杀虫活性进行室内毒力测试.单晶衍射结果表明，杀虫剂环氧虫啉属于三斜晶系、P\|1空间群.室内毒力测定结果表明，环氧虫啉对甘蓝蚜虫的LC50为0.044 g/mL，以吡虫啉为标准，环氧虫啉的相对毒力指数为1.2.新烟碱类杀虫剂环氧虫啉杀虫活性高，具有较好的应用价值.
Abstract:
Huanyangchonglin was invented by Wuhan Institute Technology and Wuhan Zhongxin Chemical Co.Ltd..To promote the development and application,huanyangchonglin was synthesized in one pot via the reaction of epichlorohydrin and 2\|nitroaminoimidazolidine and its single crystal was made by the methods of purification and evolution. The structure of huanyangchonglin was characterized by elemental analysis,nuclear magnetic resonance spectrum,mass spectrometry and X\|ray diffraction patterns. Huanyangchonglin belongs to triclinic,and its space group is P\|1. Insecticidal test shows that the LC50 of huanyangchonglin is 0.044 g/mL against brevicoryne brassicase linn in vitro and the toxicity index of it is 1.2 compared with imidacloprid. Huanyangchonglin has good application value with high insecticidal activity against brevicoryne brassicase linn in vitro.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期：20130902基金项目：武汉市科技攻关项目（201020622248）作者简介：巨修练（1959\|），男，陕西乾县人，教授，博士，博士研究生导师.研究方向：计算机药物辅助设计、新农药研发、生物活性测试
更新日期/Last Update: 2014-01-07